THE THYROID TRUST, THYROID FRIENDS
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Research References

This page lists significant thyroid studies and reviews published in respected medical journals. It is far from exhaustive of course and does not try to be. The references will be added to over time.  
Please Let us know if you are aware of a study you think should be included here.   

To find out about and get involved in new research studies which are taking place now - visit our Get Involved in Research page. 

Covid-19 and thyroid function 

An important new study looking at thyroid function tests in Covid19 patients was published, in the Journal of Clinical Endocrinology and Metabolism, on 12th November 2020, showing TSH and T4 levels are lowered during Covid19 but return to their original levels once the patient is followed up with afterwards. TSH and thyroid hormone levels are affected by many illnesses which is why you would not normally have a thyroid function test when you know you have a virus or infection of any kind. 

https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgaa830/5979483 
​

Graves' Hyperthyroidism

Treatments for Graves' Disease have remained largely unchanged for 70 yrs and sometimes don't work, or can lead to lifelong treatment for hypothyroidism, but now new options are being investigated.  This review, by Laura C Lane, Tim Cheetham, Petros Perros and Simon H S Pearce, provides a comprehensive summary of the recent advances and various stages of development of the novel therapeutic approaches to treat Graves’ hyperthyroidism. by  https://academic.oup.com/edrv/article/41/6/bnaa022/5897403#
​

Hypothyroidism

An important new article, Time for a reassessment of the treatment of hypothyroidism, by John E. M. Midgley,  with Anthony D. Toft, Rolf Larisch, Johannes W. Dietrich and Rudolf Hoermann was published in BMC Endocrine Disorders, 18th April 2019. 

The following studies were mentioned in Dr Anthony Toft's talk at The Thyroid Trust November 2018 Information Event. 
  1. Jonklaas J, et al 2018 Physician choice of hypothyroidism therapy: influence of patient characteristics. Thyroid 28: 1416-1424.
  2. Peterson AJ, et al 2018 An online survey of hypothyroid patients demonstrates prominent dissatisfaction. Thyroid 28: 707-721.​​

Thyroid and Nutrition

The following study references have been provided by Professor Margaret Rayman, one of the speakers at our November 2019 event on nutrition and thyroid disease. Read our interview with Margaret. 
  1. Rayman MP. Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease. Proceedings of the Nutrition Society, 2019; 78: 34–44.​
  2. Jo S et al. Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain. The Journal of Clinical Investigation, 2019; 129:230-245.  
  3. Hernandez A. Cognitive function in hypothyroidism: what is that deiodinase again? The Journal of Clinical Investigation, 2019; 129:55-57. 
  4. Carlé A et al. Hypothyroid Patients Encoding Combined MCT10 and DIO2 Gene Polymorphisms May Prefer L-T3 + L-T4 Combination Treatment – Data Using a Blind, Randomized, Clinical Study. European Thyroid Journal, 2017; 6:143–151. 

for everyone affected by thyroid disease


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15 Great College Street, London, SW1P 3RX

The Thyroid Trust is also known as TTT and Thyroid Friends Network,
Registered Charity Number 1183292
Registered Address: 15 GREAT COLLEGE STREET, LONDON, SW1P 3RX
Copyright asserted 2019 - Our consititution and all policy documents can be viewed on request. 
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  • Home
  • About
    • Our Team
    • Annual Report
    • Awareness Videos
    • What people say about us
    • Work for us
  • Events
    • TTT Events Listings
    • International Thyroid Awareness Week 2022
    • Thyroid Cancer Awareness Month
    • Events by other organisations
    • Meeting reports
  • Information
    • Covid-19
    • News >
      • Press Releases
      • Media Coverage
      • MHRA news
      • Women's Health Strategy
      • Funding News >
        • November 2019 Funding News
        • Summer 2020
    • T3 News and Resources >
      • Liothyronine Dossier 2018
      • A GP writes
      • Scottish Parliament
    • Information Videos
    • Expert Insight
    • Research >
      • Research Participation
      • Research References
    • NICE Guidelines >
      • NICE Guideline Thyroid Cancer
    • Mother Baby Iodine
    • Patient Stories >
      • 24 Questions Videos
      • Michael Rosen
      • Vroni
      • Vicky
      • Karen
      • Michelle
      • Kelly
      • Pamela
      • Helga
      • Mary
      • Submit Your Story
  • Fun stuff
    • Badges
    • Butterfly Art
    • Fondant Thyroids Workshop
    • Gallery
    • Kindness Rocks
    • CAN Affirmation Cards
    • Seaside Walk 2019
  • Blog
  • Contact
    • T3 report form
  • Support Us
    • Fantastic Fundraisers
    • Butterflies Arise!
    • T-Shirts
    • Internet Shoppers
  • Donate
  • Graves Disease - Resource List